Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways

BACKGROUND: Allergen induced early phase airway response and airway plasma exudation are predominantly mediated by inflammatory mast cell mediators including histamine, cysteinyl leukotrienes (cysLTs) and thromboxane A2 (TXA2). The aim of the present study was to evaluate whether repeated allergen e...

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Bibliografiske detaljer
Main Authors: Cui, Zhi-Hua, Rådinger, Madeleine, Sjöstrand, Margareta, Lötvall, Jan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348058/
https://ncbi.nlm.nih.gov/pubmed/22439792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-7022-2-7
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