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A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Endogenous Nmnat in Maintaining Axonal Integrity

Axons damaged by acute injury, toxic insults or during neurodegenerative diseases undergo Wallerian or Wallerian-like degeneration, which is an active and orderly cellular process but the underlying mechanisms are poorly understood [1–3]. Drosophila has been proven a successful system for modeling h...

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Detalhes bibliográficos
Main Authors: Fang, Yanshan, Soares, Lorena, Teng, Xiuyin, Geary, Melissa, Bonini, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347919/
https://ncbi.nlm.nih.gov/pubmed/22425156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.01.065
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