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Links between metabolism and cancer
Metabolism generates oxygen radicals, which contribute to oncogenic mutations. Activated oncogenes and loss of tumor suppressors in turn alter metabolism and induce aerobic glycolysis. Aerobic glycolysis or the Warburg effect links the high rate of glucose fermentation to cancer. Together with gluta...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347786/ https://ncbi.nlm.nih.gov/pubmed/22549953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.189365.112 |
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