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Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole

Growing evidence indicates that glia pathology and amino-acid neurotransmitter system abnormalities contribute to the pathophysiology and possibly the pathogenesis of major depressive disorder. This study investigates changes in glial function occurring in the rat prefrontal cortex (PFC) after chron...

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Autori principali: Banasr, M, Chowdhury, GMI, Terwilliger, R, Newton, SS, Duman, RS, Behar, KL, Sanacora, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347761/
https://ncbi.nlm.nih.gov/pubmed/18825147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2008.106
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