The Sodium Channel Accessory Subunit Navβ1 Regulates Neuronal Excitability through Modulation of Repolarizing Voltage-Gated K(+) Channels

The channel pore-forming α subunit Kv4.2 is a major constituent of A-type (I(A)) potassium currents and a key regulator of neuronal membrane excitability. Multiple mechanisms regulate the properties, subcellular targeting, and cell-surface expression of Kv4.2-encoded channels. In the present study,...

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Main Authors: Marionneau, Céline, Carrasquillo, Yarimar, Norris, Aaron J., Townsend, R. Reid, Isom, Lori L., Link, Andrew J., Nerbonne, Jeanne M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347704/
https://ncbi.nlm.nih.gov/pubmed/22539834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6450-11.2012
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