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Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation

The epicardium is the primary source of coronary vascular smooth muscle cells (cVSMCs) and fibroblasts that reside in the compact myocardium. To form these epicardial-derived cells (EPDCs), the epicardium undergoes the process of epithelial to mesenchymal transition (EMT). Although several signaling...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baek, Seung Tae, Tallquist, Michelle D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347692/
https://ncbi.nlm.nih.gov/pubmed/22535408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074054
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