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Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation

The epicardium is the primary source of coronary vascular smooth muscle cells (cVSMCs) and fibroblasts that reside in the compact myocardium. To form these epicardial-derived cells (EPDCs), the epicardium undergoes the process of epithelial to mesenchymal transition (EMT). Although several signaling...

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Detalhes bibliográficos
Main Authors: Baek, Seung Tae, Tallquist, Michelle D.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347692/
https://ncbi.nlm.nih.gov/pubmed/22535408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.074054
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