Wnt5a and Wnt11 are essential for second heart field progenitor development

Wnt/β-catenin has a biphasic effect on cardiogenesis, promoting the induction of cardiac progenitors but later inhibiting their differentiation. Second heart field progenitors and expression of the second heart field transcription factor Islet1 are inhibited by the loss of β-catenin, indicating that...

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Bibliographic Details
Main Authors: Cohen, Ethan David, Miller, Mayumi F., Wang, Zichao, Moon, Randall T., Morrisey, Edward E.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
Subjects:
Development and Stem Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347685/
https://ncbi.nlm.nih.gov/pubmed/22569553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.069377
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