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Wnt5a and Wnt11 are essential for second heart field progenitor development

Wnt/β-catenin has a biphasic effect on cardiogenesis, promoting the induction of cardiac progenitors but later inhibiting their differentiation. Second heart field progenitors and expression of the second heart field transcription factor Islet1 are inhibited by the loss of β-catenin, indicating that...

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Bibliografiska uppgifter
Huvudupphovsmän: Cohen, Ethan David, Miller, Mayumi F., Wang, Zichao, Moon, Randall T., Morrisey, Edward E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347685/
https://ncbi.nlm.nih.gov/pubmed/22569553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.069377
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