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Inhibition of Ras for cancer treatment: the search continues
BACKGROUND: The RAS oncogenes (HRAS, NRAS and KRAS) comprise the most frequently mutated class of oncogenes in human cancers (33%), stimulating intensive effort in developing anti-Ras inhibitors for cancer treatment. DISCUSSION: Despite intensive effort, to date no effective anti-Ras strategies have...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347641/ https://ncbi.nlm.nih.gov/pubmed/22004085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.121 |
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