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Bacterial Synthesis and Purification of Normal and Mutant Forms of Human FGFR3 Transmembrane Segment

The fibroblast growth factor receptor 3 (FGFR3) is a protein belonging to the family of receptor tyrosine kinases. FGFR3 plays an important role in human skeletal development. Mutations in this protein, including Gly380Arg or Ala391Glu substitutions in the transmembrane (TM) region, can cause differ...

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Autori principali: Goncharuk, S.A., Goncharuk, M.V., Mayzel, M.L., Lesovoy, D.M., Chupin, V.V., Bocharov, 
E.V., Arseniev, A.S., Kirpichnikov, M.P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: A.I. Gordeyev 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347607/
https://ncbi.nlm.nih.gov/pubmed/22649697
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