Hereditary Breast-Ovarian Cancer Syndrome in Russia

Hereditary breast-ovarian cancer syndrome contributes to as much as 5–7% of breast cancer (BC) and 10–15% of ovarian cancer (OC) incidence. Mutations in the “canonical” genesBRCA1andBRCA2occur in 20–30% of affected pedigrees. In addition toBRCA1andBRCA2 mutations, germ-line lesions in theCHEK2,NBS1,...

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Main Authors: Sokolenko, A.P., Iyevleva, A.G., Mitiushkina, N.V., Suspitsin, E.N., Preobrazhenskaya, E.`V., Kuligina, E.Sh., Voskresenskiy, D.A., Lobeiko, O.S., Krylova, N.Yu., Gorodnova, T.V., Buslov, K.G., Bit-Sava, E.M., Dolmatov, G.D., Porhanova, N.V., Polyakov, I.S., Abysheva, S.N., Katanugina, A.S., Baholdin, D.V., Yanus, G.A., Togo, A.V., Moiseyenko, V.M., Maximov, S.Ya., Semiglazov, V.F., Imyanitov, E.N.
Format: Artigo
Sprog:Inglês
Udgivet: A.I. Gordeyev 2010
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347586/
https://ncbi.nlm.nih.gov/pubmed/22649661
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