The Staphylococcus aureus Alpha-Toxin Perturbs the Barrier Function in Caco-2 Epithelial Cell Monolayers by Altering Junctional Integrity

Increased microvascular permeability is a hallmark of sepsis and septic shock. Intestinal mucosal dysfunction may allow translocation of bacteria and their products, thereby promoting sepsis and inflammation. Although Staphylococcus aureus alpha-toxin significantly contributes to sepsis and perturbs...

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Detalhes bibliográficos
Main Authors: Kwak, Young-Keun, Vikström, Elena, Magnusson, Karl-Eric, Vécsey-Semjén, Beatrix, Colque-Navarro, Patricia, Möllby, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347457/
https://ncbi.nlm.nih.gov/pubmed/22354024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00001-12
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