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Decreased Neuraminidase Activity Is Important for the Adaptation of H5N1 Influenza Virus to Human Airway Epithelium

Highly pathogenic avian H5N1 influenza viruses remain a pandemic threat. Antiviral drugs such as neuraminidase (NA) inhibitors will be crucial for disease control in the event of a pandemic. Should drug-resistant H5N1 viruses develop, all defense strategies will be compromised. To determine the like...

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Hlavní autoři: Ilyushina, Natalia A., Bovin, Nicolai V., Webster, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347354/
https://ncbi.nlm.nih.gov/pubmed/22379077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06774-11
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