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Both influenza hemagglutinin and polymerase acidic genes are important for delayed pandemic 2009 H1N1 virus clearance in the ferret model

We previously showed that a pandemic virus, A/Tennessee/560/09(H1N1), had the potential to adapt to human bronchial epithelial cells by the acquisition of hemagglutinin (HA) K154Q and polymerase acidic (PA) protein L295P mutations that conferred a more virulent phenotype. To better elucidate the rol...

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書誌詳細
主要な著者: Ducatez, Mariette F., Ilyushina, Natalia A., Fabrizio, Thomas P., Rehg, Jerold E., Bovin, Nicolai V., Webster, Robert G., Webby, Richard J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426312/
https://ncbi.nlm.nih.gov/pubmed/22809692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.06.018
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