Hepatitis C Virus Nonstructural Protein 5B Is Involved in Virus Morphogenesis

The p7 protein of hepatitis C virus (HCV) is a viroporin that is dispensable for viral genome replication but plays a critical role in virus morphogenesis. In this study, we generated a JFH1-based intergenotypic chimeric genome that encoded a heterologous genotype 1b (GT1b) p7. The parental intergen...

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Hlavní autoři: Gouklani, Hamed, Bull, Rowena A., Beyer, Claudia, Coulibaly, Fasséli, Gowans, Eric J., Drummer, Heidi E., Netter, Hans J., White, Peter A., Haqshenas, Gholamreza
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347352/
https://ncbi.nlm.nih.gov/pubmed/22345449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07089-11
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