Restored PB1-F2 in the 2009 Pandemic H1N1 Influenza Virus Has Minimal Effects in Swine

PB1-F2 is an 87- to 90-amino-acid-long protein expressed by certain influenza A viruses. Previous studies have shown that PB1-F2 contributes to virulence in the mouse model; however, its role in natural hosts—pigs, humans, or birds—remains largely unknown. Outbreaks of domestic pigs infected with th...

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Main Authors: Pena, Lindomar, Vincent, Amy L., Loving, Crystal L., Henningson, Jamie N., Lager, Kelly M., Lorusso, Alessio, Perez, Daniel R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347308/
https://ncbi.nlm.nih.gov/pubmed/22379102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00134-12
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