The Double-Stranded RNA Bluetongue Virus Induces Type I Interferon in Plasmacytoid Dendritic Cells via a MYD88-Dependent TLR7/8-Independent Signaling Pathway

Dendritic cells (DCs), especially plasmacytoid DCs (pDCs), produce large amounts of alpha/beta interferon (IFN-α/β) upon infection with DNA or RNA viruses, which has impacts on the physiopathology of the viral infections and on the quality of the adaptive immunity. However, little is known about the...

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Autors principals: Ruscanu, Suzana, Pascale, Florentina, Bourge, Mickael, Hemati, Behzad, Elhmouzi-Younes, Jamila, Urien, Céline, Bonneau, Michel, Takamatsu, Haru, Hope, Jayne, Mertens, Peter, Meyer, Gilles, Stewart, Meredith, Roy, Polly, Meurs, Eliane F., Dabo, Stéphanie, Zientara, Stéphan, Breard, Emmanuel, Sailleau, Corinne, Chauveau, Emilie, Vitour, Damien, Charley, Bernard, Schwartz-Cornil, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347300/
https://ncbi.nlm.nih.gov/pubmed/22438548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06716-11
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