The Double-Stranded RNA Bluetongue Virus Induces Type I Interferon in Plasmacytoid Dendritic Cells via a MYD88-Dependent TLR7/8-Independent Signaling Pathway

Dendritic cells (DCs), especially plasmacytoid DCs (pDCs), produce large amounts of alpha/beta interferon (IFN-α/β) upon infection with DNA or RNA viruses, which has impacts on the physiopathology of the viral infections and on the quality of the adaptive immunity. However, little is known about the...

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Main Authors: Ruscanu, Suzana, Pascale, Florentina, Bourge, Mickael, Hemati, Behzad, Elhmouzi-Younes, Jamila, Urien, Céline, Bonneau, Michel, Takamatsu, Haru, Hope, Jayne, Mertens, Peter, Meyer, Gilles, Stewart, Meredith, Roy, Polly, Meurs, Eliane F., Dabo, Stéphanie, Zientara, Stéphan, Breard, Emmanuel, Sailleau, Corinne, Chauveau, Emilie, Vitour, Damien, Charley, Bernard, Schwartz-Cornil, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347300/
https://ncbi.nlm.nih.gov/pubmed/22438548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06716-11
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