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The PSAP Motif within the ORF3 Protein of an Avian Strain of the Hepatitis E Virus Is Not Critical for Viral Infectivity In Vivo but Plays a Role in Virus Release

The ORF3 protein of hepatitis E virus (HEV) is a multifunctional protein important for virus replication. The ORF3 proteins from human, swine, and avian strains of HEV contain a conserved PXXP amino acid motif, resembling either Src homology 3 (SH3) cell signaling interaction motifs or “late domains...

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Detalhes bibliográficos
Main Authors: Kenney, Scott P., Pudupakam, R. S., Huang, Yao-Wei, Pierson, F. William, LeRoith, Tanya, Meng, Xiang-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347299/
https://ncbi.nlm.nih.gov/pubmed/22438540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06711-11
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