Identification of Host-Chromosome Binding Sites and Candidate Gene Targets for Kaposi's Sarcoma-Associated Herpesvirus LANA

LANA is essential for tethering the Kaposi's sarcoma-associated herpesvirus (KSHV) genome to metaphase chromosomes and for modulating host-cell gene expression, but the binding sites in the host-chromosome remain unknown. Here, we use LANA-specific chromatin immunoprecipitation coupled with hig...

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Autori principali: Lu, Fang, Tsai, Kevin, Chen, Horng-Shen, Wikramasinghe, Priyankara, Davuluri, Ramana V., Showe, Louise, Domsic, John, Marmorstein, Ronen, Lieberman, Paul M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347294/
https://ncbi.nlm.nih.gov/pubmed/22419807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07216-11
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