Generation of an HIV-1-Resistant Immune System with CD34(+) Hematopoietic Stem Cells Transduced with a Triple-Combination Anti-HIV Lentiviral Vector

HIV gene therapy has the potential to offer an alternative to the use of current small-molecule antiretroviral drugs as a treatment strategy for HIV-infected individuals. Therapies designed to administer HIV-resistant stem cells to an infected patient may also provide a functional cure, as observed...

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Autors principals: Walker, Jon E., Chen, Rachel X., McGee, Jeannine, Nacey, Catherine, Pollard, Richard B., Abedi, Mehrdad, Bauer, Gerhard, Nolta, Jan A., Anderson, Joseph S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347262/
https://ncbi.nlm.nih.gov/pubmed/22398281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06300-11
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