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Hepatitis E Virus Replication Requires an Active Ubiquitin-Proteasome System

The mechanism of hepatitis E virus (HEV) replication remains largely unknown. Here we demonstrate that HEV replication requires an active ubiquitin-proteasome system and that proteasome inhibitors affect HEV replication, possibly by inhibition of viral transcription or/and translation without a sign...

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Detalhes bibliográficos
Main Authors: Karpe, Yogesh A., Meng, Xiang-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347252/
https://ncbi.nlm.nih.gov/pubmed/22438536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07039-11
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