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Genomic Comparison between a Virulent Type A1 Strain of Francisella tularensis and Its Attenuated O-Antigen Mutant

We report the complete genome sequences of TI0902, a highly virulent type A1 strain, and TIGB03, a related, attenuated chemical mutant strain. Compared to the wild type, the mutant strain had 45 point mutations and a 75.9-kb duplicated region that had not been previously observed in Francisella spec...

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Bibliografiske detaljer
Main Authors: Modise, Thero, Ryder, Cheryl, Mane, Shrinivasrao P., Bandara, Aloka B., Jensen, Roderick V., Inzana, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347185/
https://ncbi.nlm.nih.gov/pubmed/22535949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00152-12
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