Isolation and Mutagenesis of a Capsule-Like Complex (CLC) from Francisella tularensis, and Contribution of the CLC to F. tularensis Virulence in Mice

BACKGROUND: Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been postulated to be present around F. tularensis ba...

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Detalhes bibliográficos
Main Authors: Bandara, Aloka B., Champion, Anna E., Wang, Xiaoshan, Berg, Gretchen, Apicella, Michael A., McLendon, Molly, Azadi, Parastoo, Snyder, D. Scott, Inzana, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081320/
https://ncbi.nlm.nih.gov/pubmed/21544194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019003
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