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The rcbA Gene Product Reduces Spontaneous and Induced Chromosome Breaks in Escherichia coli

Elevated levels of DnaA cause excessive initiation, which leads to an increased level of double-strand breaks that are proposed to arise when newly formed replication forks collide from behind with stalled or collapsed forks. These double-strand breaks are toxic in mutants that are unable to repair...

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Detalhes bibliográficos
Main Authors: Felczak, Magdalena M., Kaguni, Jon M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347072/
https://ncbi.nlm.nih.gov/pubmed/22343303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06390-11
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