The Variable Subdomain of Escherichia coli SecA Functions To Regulate SecA ATPase Activity and ADP Release

Bacterial SecA proteins can be categorized by the presence or absence of a variable subdomain (VAR) located within nucleotide-binding domain II of the SecA DEAD motor. Here we show that VAR is dispensable for SecA function, since the VAR deletion mutant secAΔ519–547 displayed a wild-type rate of cel...

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Main Authors: Das, Sanchaita, Grady, Lorry M., Michtavy, Jennifer, Zhou, Yayan, Cohan, Frederick M., Hingorani, Manju M., Oliver, Donald B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347061/
https://ncbi.nlm.nih.gov/pubmed/22389482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00039-12
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