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Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

Identification of new tetrodotoxin (TTX) analogs from TTX-possessing animals might provide insight into its biosynthesis and metabolism. In this study, four new analogs, 8-epi-5,6,11-trideoxyTTX, 4,9-anhydro-8-epi-5,6,11-trideoxyTTX, 1-hydroxy-8-epi-5,6,11-trideoxyTTX, and 1-hydroxy-4,4a-anhydro-8-e...

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Autors principals: Kudo, Yuta, Yasumoto, Takeshi, Konoki, Keiichi, Cho, Yuko, Yotsu-Yamashita, Mari
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347022/
https://ncbi.nlm.nih.gov/pubmed/22611361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10030655
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