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Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

Identification of new tetrodotoxin (TTX) analogs from TTX-possessing animals might provide insight into its biosynthesis and metabolism. In this study, four new analogs, 8-epi-5,6,11-trideoxyTTX, 4,9-anhydro-8-epi-5,6,11-trideoxyTTX, 1-hydroxy-8-epi-5,6,11-trideoxyTTX, and 1-hydroxy-4,4a-anhydro-8-e...

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Detalhes bibliográficos
Main Authors: Kudo, Yuta, Yasumoto, Takeshi, Konoki, Keiichi, Cho, Yuko, Yotsu-Yamashita, Mari
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347022/
https://ncbi.nlm.nih.gov/pubmed/22611361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10030655
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