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Computational Modeling and Numerical Methods for Spatiotemporal Calcium Cycling in Ventricular Myocytes

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex network of spatially distributed organelles, such as sarcoplasmic reticulum (SR), mitochondria, and myofibrils. In this study, we present a mathematical model of intracellular Ca cycling and numerical and compu...

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Bibliographic Details
Main Authors: Nivala, Michael, de Lange, Enno, Rovetti, Robert, Qu, Zhilin
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346978/
https://ncbi.nlm.nih.gov/pubmed/22586402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00114
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