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Enhanced CBir1-specific innate and adaptive immune responses in Crohn’s disease

CBir1 is a dominant antigen with a role in innate and adaptive immunity in mouse models of colitis and antibodies to CBir1 are associated with severe human Crohn’s disease. Our aim was to determine whether CBir1 stimulates innate and antigen-specific T-cell responses in Crohn’s disease. We demonstra...

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Hlavní autoři: Shen, Chong, Landers, Carol J., Derkowski, Carrie, Elson, Charles O., Targan, Stephan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346963/
https://ncbi.nlm.nih.gov/pubmed/18825772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20645
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