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Human lymphohematopoietic reconstitution and immune function in immunodeficient mice receiving cotransplantation of human thymic tissue and CD34(+) cells

Small animal models with functional human lymphohematopoietic systems are highly valuable for the study of human immune function under physiological and pathological conditions. Over the last two decades, numerous efforts have been devoted towards the development of such humanized mouse models. This...

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Detalhes bibliográficos
Main Authors: Hu, Zheng, Yang, Yong-Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346882/
https://ncbi.nlm.nih.gov/pubmed/22307039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.63
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