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Macrophages prevent human red blood cell reconstitution in immunodeficient mice

An animal model supporting human erythropoiesis will be highly valuable for assessing the biologic function of human RBCs under physiologic and disease settings, and for evaluating protocols of in vitro RBC differentiation. Herein, we analyzed human RBC reconstitution in NOD/SCID or NOD/SCID/γc(−/−)...

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Autors principals: Hu, Zheng, Van Rooijen, Nico, Yang, Yong-Guang
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228505/
https://ncbi.nlm.nih.gov/pubmed/21926352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-321414
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