Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis

Multiple sclerosis (MS) is a complex disease of the central nervous system of unknown etiology. The human leukocyte antigen (HLA) locus on chromosome 6 confers a considerable part of the susceptibility to MS, and the most important factor is the class II allele HLA-DRB1*15:01. In addition, we and ot...

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Autores principales: Link, Jenny, Kockum, Ingrid, Lorentzen, Åslaug R., Lie, Benedicte A., Celius, Elisabeth G., Westerlind, Helga, Schaffer, Marie, Alfredsson, Lars, Olsson, Tomas, Brynedal, Boel, Harbo, Hanne F., Hillert, Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346735/
https://ncbi.nlm.nih.gov/pubmed/22586495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036779
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