Genomewide linkage study of modifiers of LRRK2-related Parkinson’s disease

BACKGROUND: Mutations in the leucine-rich repeat kinase 2 gene (LRRK2), located at 12q12, are the most common known genetic causes of Parkinson’s disease (PD). Studies of LRRK2 mutation carriers have shown incomplete and age-dependent penetrance and previous studies have suggested that inherited sus...

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Auteurs principaux: LATOURELLE, JEANNE C., HENDRICKS, AUDREY E., PANKRATZ, NATHAN, WILK, JEMMA B., HALTER, CHERYL, NICHOLS, WILLIAM C., GUSELLA, JAMES F., DESTEFANO, ANITA L., MYERS, RICHARD H., FOROUD, TATIANA
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346677/
https://ncbi.nlm.nih.gov/pubmed/21661047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.23781
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