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Genetic and Biochemical Characterization of a Novel Metallo-β-Lactamase, TMB-1, from an Achromobacter xylosoxidans Strain Isolated in Tripoli, Libya

An Achromobacter xylosoxidans strain from the Tripoli central hospital produced a unique metallo-β-lactamase, designated TMB-1, which is related to DIM-1 (62%) and GIM-1 (51%). bla(TMB-1) was embedded in a class 1 integron and located on the chromosome. The TMB-1 β-lactamase has lower k(cat) values...

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Main Authors: El Salabi, Allaaeddin, Borra, Pardha Saradhi, Toleman, Mark A., Samuelsen, Ørjan, Walsh, Timothy R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346670/
https://ncbi.nlm.nih.gov/pubmed/22290947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05640-11
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