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Biochemical Characterization of the Acquired Metallo-β-Lactamase SPM-1 from Pseudomonas aeruginosa

SPM-1 is a new metallo-β-lactamase recently identified in Pseudomonas aeruginosa strain 48-1997A, isolated in Sao Paulo, Brazil. Kinetic analysis demonstrated that SPM-1 has a broad hydrolytic profile across a wide range of β-lactam antibiotics. Considerable variation was observed within the penicil...

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Detalhes bibliográficos
Main Authors: Murphy, Tanya A., Simm, Alan M., Toleman, Mark A., Jones, Ronald N., Walsh, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151762/
https://ncbi.nlm.nih.gov/pubmed/12543663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.582-587.2003
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