Fitness Cost and Interference of Arm/Rmt Aminoglycoside Resistance with the RsmF Housekeeping Methyltransferases

Arm/Rmt methyltransferases have emerged recently in pathogenic bacteria as enzymes that confer high-level resistance to 4,6-disubstituted aminoglycosides through methylation of the G1405 residue in the 16S rRNA (like ArmA and RmtA to -E). In prokaryotes, nucleotide methylations are the most common t...

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Bibliografiset tiedot
Päätekijät: Gutierrez, Belen, Escudero, Jose A., San Millan, Alvaro, Hidalgo, Laura, Carrilero, Laura, Ovejero, Cristina M., Santos-Lopez, Alfonso, Thomas-Lopez, Daniel, Gonzalez-Zorn, Bruno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Mechanisms of Resistance
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346654/
https://ncbi.nlm.nih.gov/pubmed/22330907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06066-11
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