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Phytosphingosine-1-Phosphate Is a Signaling Molecule Involved in Miconazole Resistance in Sessile Candida albicans Cells

Previous research has shown that 1% to 10% of sessile Candida albicans cells survive treatment with high doses of miconazole (a fungicidal imidazole). In the present study, we investigated the involvement of sphingolipid biosynthetic intermediates in this survival. We observed that the LCB4 gene, co...

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Hlavní autoři: Vandenbosch, Davy, Bink, Anna, Govaert, Gilmer, Cammue, Bruno P. A., Nelis, Hans J., Thevissen, Karin, Coenye, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346612/
https://ncbi.nlm.nih.gov/pubmed/22354293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05106-11
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