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Phytosphingosine-1-Phosphate Is a Signaling Molecule Involved in Miconazole Resistance in Sessile Candida albicans Cells

Previous research has shown that 1% to 10% of sessile Candida albicans cells survive treatment with high doses of miconazole (a fungicidal imidazole). In the present study, we investigated the involvement of sphingolipid biosynthetic intermediates in this survival. We observed that the LCB4 gene, co...

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Autori principali: Vandenbosch, Davy, Bink, Anna, Govaert, Gilmer, Cammue, Bruno P. A., Nelis, Hans J., Thevissen, Karin, Coenye, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346612/
https://ncbi.nlm.nih.gov/pubmed/22354293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05106-11
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