Induction of Holomycin Production and Complex Metabolic Changes by the argR Mutation in Streptomyces clavuligerus NP1

In bacteria, arginine biosynthesis is tightly regulated by a universally conserved regulator, ArgR, which regulates the expression of arginine biosynthetic genes, as well as other important genes. Disruption of argR in Streptomyces clavuligerus NP1 resulted in complex phenotypic changes in growth an...

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Bibliografiske detaljer
Main Authors: Yin, Hua, Xiang, Sihai, Zheng, Jianting, Fan, Keqiang, Yu, Tingting, Yang, Xu, Peng, Yanfeng, Wang, Haibin, Feng, Deqin, Luo, Yuanming, Bai, Hua, Yang, Keqian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346449/
https://ncbi.nlm.nih.gov/pubmed/22344669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.07699-11
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