Induction of Holomycin Production and Complex Metabolic Changes by the argR Mutation in Streptomyces clavuligerus NP1

In bacteria, arginine biosynthesis is tightly regulated by a universally conserved regulator, ArgR, which regulates the expression of arginine biosynthetic genes, as well as other important genes. Disruption of argR in Streptomyces clavuligerus NP1 resulted in complex phenotypic changes in growth an...

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Detalhes bibliográficos
Principais autores: Yin, Hua, Xiang, Sihai, Zheng, Jianting, Fan, Keqiang, Yu, Tingting, Yang, Xu, Peng, Yanfeng, Wang, Haibin, Feng, Deqin, Luo, Yuanming, Bai, Hua, Yang, Keqian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346449/
https://ncbi.nlm.nih.gov/pubmed/22344669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.07699-11
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