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Molecular Determinants of the Cofactor Specificity of Ribitol Dehydrogenase, a Short-Chain Dehydrogenase/Reductase

Ribitol dehydrogenase from Zymomonas mobilis (ZmRDH) catalyzes the conversion of ribitol to d-ribulose and concomitantly reduces NAD(P)(+) to NAD(P)H. A systematic approach involving an initial sequence alignment-based residue screening, followed by a homology model-based screening and site-directed...

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Detalhes bibliográficos
Main Authors: Moon, Hee-Jung, Tiwari, Manish Kumar, Singh, Ranjitha, Kang, Yun Chan, Lee, Jung-Kul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346437/
https://ncbi.nlm.nih.gov/pubmed/22344653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.07751-11
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