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The Trypanosomatid-Specific N Terminus of RPA2 Is Required for RNA Polymerase I Assembly, Localization, and Function

African trypanosomes are the only organisms known to use RNA polymerase I (pol I) to transcribe protein-coding genes. These genes include VSG, which is essential for immune evasion and is transcribed from an extranucleolar expression site body (ESB). Several trypanosome pol I subunits vary compared...

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Autori principali: Daniels, Jan-Peter, Gull, Keith, Wickstead, Bill
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346432/
https://ncbi.nlm.nih.gov/pubmed/22389385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00036-12
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