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Heparin-Binding Hemagglutinin Induces IFN-γ(+) IL-2(+) IL-17(+) Multifunctional CD4(+) T Cells during Latent but Not Active Tuberculosis Disease
The mycobacterial heparin-binding hemagglutinin (HBHA) protein induces a potent gamma interferon (IFN-γ) response in latent tuberculosis (TB) infection and is a candidate vaccine and diagnostic antigen. We have assessed HBHA-specific intracellular IFN-γ, interleukin-2 (IL-2), and IL-17 production by...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346316/ https://ncbi.nlm.nih.gov/pubmed/22461525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00047-12 |
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