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Toward an In Vivo Dissolution Methodology: A Comparison of Phosphate and Bicarbonate Buffers
PURPOSE: To evaluate the difference between the pharmaceutical phosphate buffers and the gastrointestinal bicarbonates in dissolution of ketoprofen and indomethacin, to illustrate the dependence of buffer differential on biopharmaceutical properties of BCS II weak acids, and to recommend phosphate b...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346296/ https://ncbi.nlm.nih.gov/pubmed/19183104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800148u |
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