Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence

BACKGROUND AND PURPOSE: Oxidative stress plays a critical role in liver fibrogenesis. Reactive oxygen species (ROS) stimulate hepatic stellate cells (HSCs), and ROS-mediated increases in calcium influx further increase ROS production. Azelnidipine is a calcium blocker that has been shown to have ant...

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Detalhes bibliográficos
Main Authors: Ohyama, T, Sato, K, Kishimoto, K, Yamazaki, Y, Horiguchi, N, Ichikawa, T, Kakizaki, S, Takagi, H, Izumi, T, Mori, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346246/
https://ncbi.nlm.nih.gov/pubmed/21790536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01599.x
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