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Positron Emission Tomography and Neuropathologic Estimates of Fibrillar Amyloid-β in a Patient With Down Syndrome and Alzheimer Disease

BACKGROUND: Down syndrome appears to be associated with a virtually certain risk of fibrillar amyloid-β (Aβ) pathology by the age of 40 and a very high risk of dementia at older ages. The positron emission tomography (PET) ligand florbetapir F18 has been shown to characterize fibrillar Aβ in the liv...

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Detalhes bibliográficos
Main Authors: Sabbagh, Marwan N., Fleisher, Adam, Chen, Kewei, Rogers, Joseph, Berk, Camryn, Reiman, Eric, Pontecorvo, Michael, Mintun, Mark, Skovronsky, Daniel, Jacobson, Sandra A., Sue, Lucia I., Liebsack, Carolyn, Charney, Albert S., Cole, Lauren, Belden, Christine, Beach, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346179/
https://ncbi.nlm.nih.gov/pubmed/22084131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.535
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