Substrate-selective and Calcium-independent Activation of CaMKII by α-Actinin

Protein-protein interactions are thought to modulate the efficiency and specificity of Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) signaling in specific subcellular compartments. Here we show that the F-actin-binding protein α-actinin targets CaMKIIα to F-actin in cells by binding t...

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Bibliographic Details
Main Authors: Jalan-Sakrikar, Nidhi, Bartlett, Ryan K., Baucum, Anthony J., Colbran, Roger J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346149/
https://ncbi.nlm.nih.gov/pubmed/22427672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351817
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