Reversal of Diabetes Through Gene Therapy of Diabetic Rats by Hepatic Insulin Expression via Lentiviral Transduction

Due to shortage of donor tissue a cure for type 1 diabetes by pancreas organ or islet transplantation is an option only for very few patients. Gene therapy is an alternative approach to cure the disease. Insulin generation in non-endocrine cells through genetic engineering is a promising therapeutic...

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Detalhes bibliográficos
Main Authors: Elsner, Matthias, Terbish, Taivankhuu, Jörns, Anne, Naujok, Ortwin, Wedekind, Dirk, Hedrich, Hans-Jürgen, Lenzen, Sigurd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345991/
https://ncbi.nlm.nih.gov/pubmed/22354377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.8
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